Chronic hepatitis C: This and the new era of treatment
Open Access
- 1 January 2016
- journal article
- review article
- Published by Baishideng Publishing Group Inc. in World Journal of Hepatology
- Vol. 8 (2), 92-106
- https://doi.org/10.4254/wjh.v8.i2.92
Abstract
Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in approximately 90% of cases. In the near future further progress will be achieved with the use of pan-genotypic drugs with high efficacy but without side effects.Keywords
This publication has 141 references indexed in Scilit:
- Hepatitis C virus host cell entryCurrent Opinion in Virology, 2012
- An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver DiseasesHepatology, 2011
- Boceprevir for Previously Treated Chronic HCV Genotype 1 InfectionNew England Journal of Medicine, 2011
- Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication CompartmentCell Host & Microbe, 2011
- Factors That Determine the Development and Progression of Gastroesophageal Varices in Patients With Chronic Hepatitis CGastroenterology, 2010
- Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease ProgressionGastroenterology, 2010
- A genome-wide genetic screen for host factors required for hepatitis C virus propagationProceedings of the National Academy of Sciences, 2009
- A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus ReplicationCell Host & Microbe, 2009
- Hepatitis C virus infection protein networkMolecular Systems Biology, 2008
- Cellular cofactors affecting hepatitis C virus infection and replicationProceedings of the National Academy of Sciences, 2007