The Croonian Lecture, 1993. The endothelium: maestro of the blood circulation
Open Access
- 29 January 1994
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 343 (1304), 225-246
- https://doi.org/10.1098/rstb.1994.0023
Abstract
The vascular endothelium plays a vital role in the control of the circulation. It metabolizes various vasoactive substances, coverts angiotensin I to angiotensin II and secretes the potent vasodilators prostacyclin and EDRF(NO) and the vasoconstrictor peptide endothelin-1. The balance between these mediators determines the responses of the cardiovascular system in diseases such as hypertension, atherosclerosis and myocardial infarction.Keywords
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