QUALITATIVE DIFFERENCES BETWEEN BRAIN AND LUNG THROMBOPLASTIC SUSPENSIONS

Abstract

Data are presented which show differences in the composition and action of brain thromboplastic suspension and lung thromboplastic suspension. These differences may be due to the presence of a clotting inhibitor in the brain suspension, and the lack of it in the lung suspension. The presence of a clot retarder in the plasma is also suggested. Further data are presented which indicate that the phenomenon of apparent brain-lung synergism may be due to dilution of the inhibitor in the brain suspension by the lung suspension, which is apparently free of this inhibitor. The effect of the inhibitor in brain thromboplastic suspension on the one-stage methods which employ diluted plasma is briefly discussed.