IN VITRO STUDIES OF MAMMALIAN SOMATIC CELL VARIATION
Open Access
- 1 February 1963
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 117 (2), 259-265
- https://doi.org/10.1084/jem.117.2.259
Abstract
The isoantigenic phenotype of the H-2 locus has been detected by isohemagglutinin absorption in a line of mouse lymphoma cells growing continuously in culture for six years and in two established lines of fibroblastic mouse cells growing continously in culture for one year. Quantitative absorption studies suggest that the concentration of H-2 isoantigens is higher in the cultured lymphoma cells than in the other two fibroblastic cell lines.Keywords
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