A controlled study of amitriptyline in the treatment of chronic pain
- 1 October 1982
- journal article
- research article
- Published by Wolters Kluwer Health in Pain
- Vol. 14 (2), 169-179
- https://doi.org/10.1016/0304-3959(82)90097-5
Abstract
A double-blind controlled cross-over study of amitriptyline vs. placebo was carried out in a group of patients referred to a multidisciplinary pain clinic for the management of chronic intractable pain for which no substantial organic cause could be demonstrated. Of 52 patients entering the 12-wk trial, 20 withdrew before completion. No differences were found in terms of global improvement on either agent. Subjective reports indicated a greater reduction in pain at 2 and 4 wk on amitriptyline, but no difference at 6 wk. None of the baseline measures was predictive of response.This publication has 16 references indexed in Scilit:
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