Abstract
The presentation, method of treatment, and follow-up of 29 apparently isolated testicular relapses in 522 boys entering Medical Research Council trials I-III are described. The need for intensive local and systemic treatment is stressed. The prognosis is poor for those with high initial leucocyte counts, and for those with testicular relapse while on chemotherapy. Among the remainder, intensive local and systemic treatment can result in some long-term remissions.