The Cloned Thrombin Receptor Is Necessary and Sufficient for Activation of Mitogen-activated Protein Kinase and Mitogenesis in Mouse Lung Fibroblasts
Open Access
- 1 August 1996
- journal article
- Published by Elsevier
- Vol. 271 (35), 21536-21541
- https://doi.org/10.1074/jbc.271.35.21536
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Role of the thrombin receptor in development and evidence for a second receptorNature, 1996
- Differential activation of p44mapk (ERK1) by α-thrombin and thrombin-receptor peptide agonistBiochemical Journal, 1993
- Thrombin receptor activating peptides: importance of the N-terminal serine and its ionization state as judged by pH dependence, nuclear magnetic resonance spectroscopy, and cleavage by aminopeptidase MBiochemistry, 1992
- MAP Kinases: Charting the Regulatory PathwaysScience, 1992
- Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.The Journal of cell biology, 1992
- Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.Molecular Biology of the Cell, 1992
- Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk.Molecular Biology of the Cell, 1992
- A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cellsBiochemical and Biophysical Research Communications, 1991
- Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationCell, 1991
- Development of 3T3‐like lines from Balb/c mouse embryo cultures: Transformation susceptibility to SV40Journal of Cellular Physiology, 1968