Abstract
The MW of the 3 double-stranded RNA (ds-RNA) components of A. foetidus virus S were re-determined by using polyacrylamide gel electrophoresis of native ds[double-stranded-RNA with ds-RNA standards and of denatured ds-RNA with single-stranded RNA standards. Good agreement between the 2 methods and confirmation that the relationship between log MW and electrophoretic mobility of ds-RNA is not linear were obtained. The new MW values (4.0-4.2 .times. 106; 2.5-2.7 .times. 106 and 0.26-0.28 .times. 106, respectively) are significantly higher than those determined previously by linear extrapolation from reovirus ds-RNA standards.