The Complete Amino Acid Sequence of Rat β2‐Microglobulin
- 1 February 1988
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 27 (2), 195-199
- https://doi.org/10.1111/j.1365-3083.1988.tb02339.x
Abstract
The primary structure of rat .beta.2-microglobulin (.beta.2m) was determined. It is a polypeptide of 99 amino acids with the following sequence: IQKTPWIQVY SHRPPENGKP NFLNCYVQF HPPQIETIELL, NKGKKIPNIE, MSDLSFSKDW, SFYLAHTEF, TPTETDVYAC, RVKHVTLKEP, KTVTWDRDM. The primary structure was determined by NH2-terminal sequence analysis together with sequence determination of one cyanogen bromide fragment and one tryptic peptide. Of other known .beta.2m sequences, rat .beta.2m is mot homologous to house .beta.2m (83% identity). The rabbit, human, and guinea pig sequences are more distant, with 24, 27, and 31% differences, respectively.This publication has 17 references indexed in Scilit:
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