The hypothermic action of carbachol in the rat brain periaqueductal grey area may involve neurotensin
Open Access
- 19 July 1986
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology
- Vol. 88 (3), 653-658
- https://doi.org/10.1111/j.1476-5381.1986.tb10247.x
Abstract
1 Neurotensin (NT) and carbachol both caused hypothermia when injected into the periaqueductal grey area (PAG) of rat brain. 2 Atropine prevented carbachol- but not NT-induced hypothermia. 3 NT-induced hypothermia was unaffected by various neurotransmitter agonists and antagonists in the PAG. 4 Both NT antibodies and thyrotrophin releasing hormone prevented carbachol hypothermia. 5 It is concluded that the hypothermic action of carbachol in the PAG is mediated via endogenous NT.This publication has 21 references indexed in Scilit:
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