Measurement of blood‐brain barrier permeability using dynamic Gd‐DTPA scanning—a comparison of methods
- 1 March 1992
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 24 (1), 174-176
- https://doi.org/10.1002/mrm.1910240119
Abstract
Two recently published methods of blood‐brain barrier permeability measurement using Gd‐DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood‐brain barrier in multiple sclerosis is in the range 1‐12·10−4s−1 © 1992 Academic Press, Inc.Keywords
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