Immunocytological localization of estrogen in human mammary carcinoma cells by horseradish—anti-horseradish peroxidase complex
- 1 January 1978
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 10 (3), 221-224
- https://doi.org/10.1002/jso.2930100308
Abstract
Tissues from 25 female and 2 male patients of mammary carcinoma were examined by the horseradish—anti‐horseradish peroxidase complex to localize the presence of estrogen. Carcinoma cells of 10 female and 2 male patients showed positive staining by this technique. The nucleus and the cytoplasmic membrane showed the reaction. This method is useful in identifying the exact location of the hormones or hormone‐like substances in the malignant cells and, perhaps, will be of great help in selecting the patients for management.Keywords
This publication has 9 references indexed in Scilit:
- The Prediction of Hormonal Dependency of Mammary CancerAnnals of Surgery, 1975
- Current status of estrogen receptors in human breast cancerCancer, 1975
- Male breast cancer—II: Metabolism of oestradiol-17β in men with breast cancerJournal of Steroid Biochemistry, 1973
- Ablation Therapy for Hormone-Dependent TumorsAnnual Review of Medicine, 1972
- Estrogen receptors in human breast cancer: 2. In vitro binding of estradiol by benign and malignant tumorsSteroids, 1971
- Estrogen receptors in human breast cancer: 1. Methodology and characterization of receptorsSteroids, 1971
- THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETESJournal of Histochemistry & Cytochemistry, 1970
- AN IMMUNOGLOBULIN-ENZYME BRIDGE METHOD FOR LOCALIZING TISSUE ANTIGENSJournal of Histochemistry & Cytochemistry, 1969
- STUDIES WITH TRITIUM-LABELLED HEXŒSTROL IN ADVANCED BREAST CANCERThe Lancet, 1961