Effect of Styrene on Hepatic Mixed Function Oxidases, Glutathione Content and Glutathione-S-Transferase Activity in Rats
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Drug and Chemical Toxicology
- Vol. 4 (3), 219-227
- https://doi.org/10.3109/01480548109018130
Abstract
Effect of styrene administration (250, 450 and 900 mg/kg orally for 7 consecutive days) on hepatic mixed function oxidase (MFO) enzyme activities, glutathione content and glutathione-S-transferase activity was observed. Activity of aryl hydrocarbon hydroxylase and aniline hydroxylase was significantly enhanced at higher doses of styrene (450 and 900 mg/kg). A significant lowering of glutathione content accompanied by the inhibition of glutathione-S-transferase activity was also noticed at the highest dose of styrene (900 mg/kg).This publication has 11 references indexed in Scilit:
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