Polyostotic Fibrous Dysplasia With Thyrotoxicosis

Abstract

FEW AUTOPSY examinations have been made on patients with polyostotic fibrous dysplasia. The present report is concerned with an individual (Fig 1) with extensive skeletal involvement with this disorder, who had a small area of cutaneous pigmentation and who, during the course of 18 years of observation, developed and was treated for thyrotoxicosis. The patient had generously willed his body to Baylor University College of Medicine and at his death, from extensive cardiopulmonary disease, autopsy was performed and the entire skeleton was reconstructed (Fig 2-4). This skeleton is now in the Anatomy Museum of that institution and is believed to be the only one in this country. The only other known skeleton of an individual with this disorder is (or was) in Berlin.¹ Report of a Case D. C. was first seen in the emergency room of the Jefferson Davis Hospital in 1947 at age 37 because of pain