Hepatic mixed‐function oxidase activity in mice treated with methylated benzenes and methylated naphthalenes
- 30 April 1977
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 2 (5), 1143-1146
- https://doi.org/10.1080/15287397709529512
Abstract
Eight methylated benzene and five methylated naphthalene compounds were injected ip into adult male mice daily for 3 days. On the fourth day livers from control and treated mice were compared with regard to weight, microsomal N‐ and O‐demethylase activity, and various spectral characteristics of microsomal cytochrome PASO. Three methylated benzenes and one methylated naphthalene produced significant increases in liver weight/body weight ratios, O‐demethylation of p‐nitroanisole, N‐demethylation of aminopyrene, or a combination of these.This publication has 7 references indexed in Scilit:
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