MULTIPLE MYELOMAS WITH TUMORLIKE AMYLOIDOSIS

Abstract
The association of amyloidosis with multiple myelomas has been noted with increasing frequency in recent years, having first been reported by Askanazy1in 1903. Magnus-Levy2in 1933 summarized the literature on the subject and collected thirty-five cases of amyloidosis complicating multiple myelomas, to which he added two more cases recently reported by Chester3and by Rosenblatt.4These were collected from 150 carefully studied cases of myeloma, or an incidence of about 25 per cent. Of these, localized masses of amyloid simulating tumors were found in ten cases. Since his article, two additional cases have been reported by Rosenheim and Wright5and by Randall.6In the former, generalized amyloid deposits were found in the bone marrow, liver and spleen, and in the latter the amyloid formed a tumor mass in the wall of the intestine causing an intestinal obstruction. Geschickter and Copeland,7in a