A comparison of tests for thyroglobulin antibody
Open Access
- 1 March 1962
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 15 (2), 153-155
- https://doi.org/10.1136/jcp.15.2.153
Abstract
A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in γ globulin was also noted from the serum electrophoretic pattern. The gel diffusion and electroprecipitin tests are shown to be comparable in their sensitivity, as are the bentonite flocculation and tanned red cell agglutination tests. The flocculation and agglutination tests were oversensitive. The latex slide test in conjunction with the electro-precipitin test is recommended for routine use in the detection of Hashimoto's disease.Keywords
This publication has 15 references indexed in Scilit:
- Thyroglobulin Antibodies in 1,297 Patients Without Thyroid DiseaseBMJ, 1961
- THYROGLOBULIN ANTIBODIES IN PATIENTS WITHOUT CLINICAL DISEASE OF THE THYROID GLANDThe Lancet, 1960
- Detection of Thyroid Antibodies using Bentonite ParticlesNature, 1959
- AN ELECTRO-PRECIPITIN TESTThe Lancet, 1958
- HUMAN AUTO-IMMUNE THYROIDITIS: SEROLOGICAL STUDIESThe Lancet, 1958
- THYROID ANTIBODIES IN MYX$OElig;DEMAThe Lancet, 1958
- PRECIPITIN TESTS IN THYROID DISEASEThe Lancet, 1957
- CHRONIC THYROIDITIS AND AUTOIMMUNIZATIONJAMA, 1957
- HASHIMOTO'S STRUMA LYMPHOMATOSA DIAGNOSTIC VALUE AND SIGNIFICANCE OF SERUM-FLOCCULATION REACTIONSThe Lancet, 1956
- Recherches sur la préparation et les propriétés de la thyroglobuline pure. IBiochimica et Biophysica Acta, 1948