An enteric-coated pancreatic enzyme preparation that works
- 30 November 1979
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 24 (12), 906-909
- https://doi.org/10.1007/bf01311943
Abstract
A new enteric-coated pancreatic enzyme preparation (microspheres) was compared with traditional enzyme tablets in six subjects with severe exocrine pancreatic insufficiency. The microspheres were found to be as effective as traditional enzyme supplements. In most patients in balance studies, the lowest fecal fat values were obtained with microsphere therapy in spite of a smaller amount of lipase administered (6015 vs 10,800–43,200 lipase units per meal). In contrast to enteric-coated tablets, microspheres can be recommended in the treatment of pancreatic steatorrhea.Keywords
This publication has 9 references indexed in Scilit:
- Sieving of Solid Food by the Canine Stomach and Sieving After Gastric SurgeryGastroenterology, 1979
- The effect of reduction of gastric acidity on the efficacy of pancreatic enzyme therapyGastroenterology, 1978
- Comparative Effects of Antacids, Cimetidine and Enteric Coating on the Therapeutic Response to Oral Enzymes in Severe Pancreatic InsufficiencyNew England Journal of Medicine, 1977
- Enzyme Replacement Therapy of Exocrine Pancreatic Insufficiency in ManNew England Journal of Medicine, 1977
- Intraluminal pH of Duodenum and Jejunum in Fasting Subjects with Normal and Abnormal Gastric Or Pancreatic FunctionScandinavian Journal of Gastroenterology, 1971
- RAPID METHOD FOR THE DETERMINATION OF FAT IN FECESJournal of Biological Chemistry, 1949