The Preparation and Teratogenic Properties of Pure Trypan Blue and its Common Contaminants
Open Access
- 1 March 1963
- journal article
- research article
- Published by The Company of Biologists in Development
- Vol. 11 (1), 175-184
- https://doi.org/10.1242/dev.11.1.175
Abstract
Starting with impure commercial samples of the dye, methods for the preparation of pure trypan blue and each of its chief contaminants are presented. The teratogenic component of the commercial mixture is shown to be the blue fraction, which is presumably trypan blue itself. The impurities are not active teratogens and do not modify qualitatively the teratogenic activity of the blue fraction.Keywords
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