Significance of urinary phenyl sulfate and phenyl glucuronide as indices of exposure to phenol
- 1 August 1986
- journal article
- research article
- Published by Springer Nature in Internationales Archiv für Arbeitsmedizin
- Vol. 58 (3), 197-202
- https://doi.org/10.1007/bf00432101
Abstract
Urine samples from subjects, who had been using phenol for treatment of chemical fiber in factories, were analysed for urinary phenyl sulfate (PhS) and phenyl glucuronide (PhG) by high-performance liquid chromatography (HPLC). The urinary levels of phenol metabolites (PhG and PhS) had a significant correlation with the environmental concentration of phenol. The urinary concentration of phenol metabolites, as a total of PhS and PhG, corresponding to 5 ppm of environmental phenol was 251 mg phenol/g creatinine.Keywords
This publication has 10 references indexed in Scilit:
- Quantitative analysis of urinary glycine conjugates by high performance liquid chromatography: excretion of hippuric acid and methylhippuric acids in the urine of subjects exposed to vapours of toluene and xylenesInternationales Archiv für Arbeitsmedizin, 1986
- High performance liquid chromatography for the quantitative determination of urinary phenylsulfate and phenylglucuronide as indices of benzene and phenol exposure in ratsInternationales Archiv für Arbeitsmedizin, 1979
- Determination of submicrogram levels of phenol in waterAnalytical Chemistry, 1973
- Quantitative relationship between atmospheric phenol vapour and phenol in the urine of workers in Bakelite factoriesOccupational and Environmental Medicine, 1972
- Evaluation of exposure to phenol: absorption of phenol vapour in the lungs and through the skin and excretion of phenol in urineOccupational and Environmental Medicine, 1971
- Urinary excretion of hippuric acid and m- or p-methylhippuric acid in the urine of persons exposed to vapours of toluene and m- or p-xylene as a test of exposureOccupational and Environmental Medicine, 1970
- Creatinine in Urine as an Index of Urinary Excretion RateHealth Physics, 1966
- URINARY EXCRETION OF PHENOL BY MEN EXPOSED TO VAPOUR OF BENZENE: A SCREENING TESTOccupational and Environmental Medicine, 1965
- Studies in detoxication. 54. The metabolism of benzene. (a) The formation of phenylglucuronide and phenylsulphuric acid from [14C]benzene. (b) The metabolism of [14C]phenolBiochemical Journal, 1953