Relationship Between the Lactic Dehydrogenase-Elevating Virus and Transplantable Murine Tumors.
- 1 April 1966
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 121 (4), 1142-1146
- https://doi.org/10.3181/00379727-121-30990
Abstract
Summary The following murine tumors were propagated serially in vitro: Sarcoma 180, Hauschka-Klein ascites tumor, and hepa-tomas 129 and 134. The lactic dehydrogenase-elevating virus initially associated with all of these tumors in vivo did not multiply in cell cultures and by serial propagation in vitro the tumors were freed from the virus. The results indicate that the relationship between the lactic dehydrogenase-elevating virus and transplantable mouse tumors is that of a common contaminant. The “virus-free” tumor cells produced tumors when implanted into mice. The growth rate and transplant-ability of these tumors was the same in normal mice and in mice infected intentionally with the virus.This publication has 3 references indexed in Scilit:
- STUDIES ON THE MULTIPLICATION AND THE PROPERTIES OF THE LACTIC DEHYDROGENASE AGENTThe Journal of Experimental Medicine, 1963
- Infection of Tumor-Bearing Mice with the Lactic Dehydrogenase AgentExperimental Biology and Medicine, 1962
- Effect of Pluronic F68 on Growth of Fibroblasts in Suspension on Rotary ShakerExperimental Biology and Medicine, 1960