Ammonium Formate in Organic Synthesis: A Versatile Agent in Catalytic Hydrogen Transfer Reductions

Abstract

Applications of ammonium formate in organic synthesis are reviewed. 1. Introduction 2. Reduction of Functional Groups 2.1. Initial Studies 2.2. Azides 2.3. Nitro Groups 2.4. Nitriles 3. Dehalogenation of Aromatic Chlorocarbons 4. Deprotection of Functional Groups 4.1. Deprotection of Polymer and Carbobenzyloxy Group from Protected Peptides 4.2. Deprotection of O-Benzyl Group 5. Regioselective Synthesis of 1-Olefins 6. Miscellaneous Applications and Other Formic Acid Derivatives 7. Conclusion