In the first part of this investigation,1based on a study of fifty-two cases, we were able to demonstrate that following the oral ingestion of standard doses of alcohol certain differences exist in the curves for the alcohol content of the blood and spinal fluid, depending on the drinking habits of the subjects. It was found that in the heavy drinkers as a group the alcohol content of the blood after ingestion increases more rapidly, reaches a higher peak and decreases more quickly than in the abstainers; the values for the group of moderate drinkers occupy an intermediate position in all three respects. As far as the curves for the alcohol content of the spinal fluid are concerned, those for the heavy drinkers rise more rapidly, reach a slightly higher peak and decline more quickly than those for the abstainers; for the moderate drinkers, however, the curves for the