DETECTION OF THE CIRCULATING ANTIBODIES TO TERATOCARCINOMA-DEFINED ANTIGENS IN PATIENTS WITH TESTICULAR-TUMORS
- 1 January 1980
- journal article
- research article
- Vol. 40 (3), 438-444
Abstract
Sera from 23 patients with primary or metastatic testicular tumors of germinal origin were tested for antibodies against teratocarcinoma-associated antigen(s) using an indirect immunofluorescence technique. Human and 129/Sv mouse sperm and mouse teratocarcionma cell line 402 AX were used as target cells. Sera (15) were identified as positive, 6 of them when tested against sperm and tumor cells. Tail staining was the most prevalent pattern of fluorescence on human and murine spermatozoa. Antibody to a common teratoma-defined antigen(s) was apparently detected in sera of patients with testicular tumors.This publication has 25 references indexed in Scilit:
- HLA and testicular cancerNature, 1979
- Human and mouse embryonal carcinoma cells in culture share an embryonic antigen (F9)Nature, 1977
- The Significance of Retroperitoneal Lymph Node Morphology in Testicular TumoursBritish Journal of Urology, 1977
- PCC4, a new cell surface antigen common to multipotential embryonal carcinoma cells, spermatozoa, and mouse early embryosDevelopmental Biology, 1977
- Mouse Teratocarcinoma and Embryonic AntigensImmunological Reviews, 1977
- Immune evaluation with skin testing.A study of testicular, prostatic, and bladder neoplasmsCancer, 1976
- Expression of teratoma-associated antigens on murine ova and early embryos: Identification of two early differentiation markersDevelopmental Biology, 1976
- Similar location of an early embryonic antigen on mouse and human spermatozoaDevelopmental Biology, 1974
- CELL SURFACE ANTIGENS OF A MOUSE TESTICULAR TERATOMAThe Journal of Experimental Medicine, 1974
- Changes in -S-S- linked structures of the sperm tail during epididymal maturation, with comparative observations in sub‐mammalian speciesJournal of Experimental Zoology, 1974