The incidence of halothane sensitivity in British pigs

Abstract

An adverse reaction in pigs to the anaesthetic halothane at approximately 8 weeks of age appears to be controlled by a single recessive gene affecting stress susceptibility, lean content and reproductive performance. In a survey of British nucleus herds, a total of 2998 pigs between 5 weeks of age and 28 kg live weight were given 3-min halothane tests during visits to 17 breeders or companies. There were no positive halothane reactions among 764 Large Whites from 7 herds. The frequency of positive reaction among 1538 Landrace from 14 herds averaged 11%, with a range from 0 to 23 % in individual herds. Frequencies in other pure breeds or synthetic lines varied from 0 to 88%. British and foreign breeds are compared, and the possibility of eliminating the halothane gene is discussed.