Effect of Stannous Fluoride Treatments on the Progression of Initial Lesions in Approximal Surfaces of Permanent Posterior Teeth

Abstract
Home use of a SnF2 dentifrice in combination with the professional application of a 10% SnF2 solution markedly retarded the growth of initial lesions over a four-year period. Overall, the SnF2 dentifrice alone showed inhibitory properties, whereas the SnF2 solution alone had no discernible effect on lesion development.