Serum Ferritin, Transferrin, Haptoglobin, and Iron in Middle- and Long-Distance Runners, Elite Rowers, and Professional Racing Cyclists*

Abstract
Serum ferritin, transferrin, haptoglobin, and iron were measured in well-trained middle- and long-distance runners, elite rowers of the West German national team, and professional racing cyclists during the summer training and the winter rest period. None of the male athletes examined, with the exception of the racing cyclists during the summer period, received oral or parenteral iron. The runners were found to have significantly lower ferritin (P < 0.0001), iron (P < 0.001), and haptoglobin values (P < 0.01) than the controls. Their transferrin levels were elevated, however not significantly. Rowers showed significantly higher ferritin levels (P < 0.01) than the controls. The reduced haptoglobin concentrations in runners are presumed to be caused by a running-induced hemolysis. It is speculated that a recurring hemoglobinuria produces diminished iron reserves in middle- and long-distance runners.