Karyotyping of bone-marrow cells in hematologic diseases
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 37 (1), 33-39
- https://doi.org/10.1007/bf00293769
Abstract
Cultures of bone-marrow cells incubated for 5 h at 4° had cells in metaphase with elongated chromosomes which were easily Giemsa banded. Colcemid was not necessary for metaphase arrest at this temperature. This technique made possible routine karyotyping of patients with leukemia and other hematological diseases in which the detection of aberrations was otherwise difficult.This publication has 5 references indexed in Scilit:
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- Non-leukemic dividing cells in the blood of leukemic patientsAmerican Journal of Hematology, 1978
- The G-banded prophase chromosomes of manHuman Genetics, 1975
- Identification of chromosome anomalies in the blastic phase of chronic myelocytic leukemia (CML) by Giemsa- and quinacrine-banding techniquesHuman Genetics, 1974
- Chromosome Preparatons of Bone Marrow Cells without PriorIn VitroCulture orIn VivoColchicine AdministrationStain Technology, 1962