Abstract
Yeast intra-cellular K ranged from 130 to 350 meq/kg cell water when K in growth medium was varied from 0.01 to 0.3 [image]. Intracellular K appeared to be distributed between a diffusible fraction, readily removed by washing, and a fixed fraction, difficult to remove by washing and relatively constant in amount. When Na in medium was varied over a similar range with K = 0.01 [image], total intracellular K was not affected, but intracellular Na increased from 10 to 260 meq/kg cell water. When medium Na was high, over 40% of the fixed K was replaced by Na.

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