Multicentric reticulohistiocytosis and malignant disease

Abstract

Multicentric reticulohistiocytosis developed in a 45 yr old woman with a 3 yr history of untreated breast carcinoma. A review of the literature revealed that malignant disease was associated with 27% of reported cases. Like adult dermatomyositis, the onset of multicentric reticulohistiocytosis should stimulate detailed investigation for an underlying neoplasm.