Insulin-Mediated Regulation of Neuronal Maturation
- 14 September 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 225 (4667), 1170-1172
- https://doi.org/10.1126/science.6089343
Abstract
Exposure to insulin increased stimulus-evoked transmission at synapses formed in culture by cholinergic retinal neurons derived from fetal rats. This effect occurred at physiological concentrations and was long lasting. The findings support the hypothesis that insulin may serve as a developmental signal to regulate the emergence of effective neurotransmission across nascent synapses.This publication has 20 references indexed in Scilit:
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