Chromosomal localization of three humanras genes by in situ molecular hybridization
- 1 March 1985
- journal article
- research article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 11 (2), 149-155
- https://doi.org/10.1007/bf01534703
Abstract
Three human rasfamily protooncogenes, c-Ki-ras-1, and c-Ki-ras-2, and N-ras,have been mapped to chromosome bands 6p11–12, 12p11.1–12.1, and 1p11–13, respectively by in situ molecular hybridization. Certain human cancers display consistent and specific alterations involving chromosomes 1, 6, and 12. The precise chromosomal localization of ras genes will permit evaluation of thepossible effect of these chromosome changes on the structure and activities of ras protooncogenes in human neoplasia.This publication has 53 references indexed in Scilit:
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