• 1 October 1968
    • journal article
    • Vol. 3 (8), 843-56
Abstract
The in vitro lymphocyte response to phytohaemagglutinin (PHA) and antigens was normal in five patients with Bruton-type agammaglobulinaemia. Lymphocytes from one infant with thymic dysplasia failed to respond to PHA. The response to PHA and antigens was variable in three patients with ataxia telangiectasia. The in vitro lymphocyte response in these patients appears to reflect the state of thymic-dependent cellular immunity or capacity for delayed hypersensitivity reactions.