Successful Treatment of Aspergillus Pneumonia in Hematologic Neoplasia

Abstract

Patients with acute leukemia and lymphoma are at increased risk of invasive pulmonary fungal infection.^{1 , 2} Among the opportunistic fungi responsible for these infections, aspergillus species are especially common.^{3 4 5 6} Invasive aspergillus pneumonia in these patients has with few exceptions been fatal, despite a number of therapeutic attempts with antifungal chemotherapy. In the two cases of aspergillus pneumonia presented below (both in patients with lymphoma) an aggressive diagnostic and therapeutic approach resulted in a successful outcome.Case ReportsCase 1. A 65-year-old woman with poorly differentiated lymphoma entered the hospital because of fever. The white-cell count was 900, with 10 per cent . . .