CSF Levels of Norepinephrine During Alcohol Withdrawal
- 1 May 1981
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 38 (5), 289-292
- https://doi.org/10.1001/archneur.1981.00510050055008
Abstract
• Cerebrospinal fluid norepinephrine (NE) levels were determined by radioenzymatic assay in 21 patients with a variety of neurological diseases and 49 patients in acute alcohol withdrawal. A second determination was made in 19 patients who had recovered from the alcohol withdrawal syndrome. Cerebrospinal fluid NE concentration was higher in the patients during alcohol withdrawal (192.3 ± 22.3 pg/mL) and decreased during recovery to 137.8 ± 15.9 pg/mL. The CSF NE level was higher in both groups than in patients with other neurological disorders. This may help to explain the adrenergic signs observed during alcohol withdrawal.This publication has 26 references indexed in Scilit:
- Receptors, Neurotransmitters and Drug ResponsesNew England Journal of Medicine, 1979
- Ethanol-induced changes in activities of adenylate cyclase, guanylate cyclase and cyclic adenosine 3′,5′-monophosphate dependent protein kinase in the brain and liverDrug and Alcohol Dependence, 1977
- Possible involvement of acetaldehyde, norepinephrine and their tetrahydroisoquinoline derivatives in the regulation of ethanol self-administrationDrug and Alcohol Dependence, 1977
- Changes in Receptor Sensitivity of the Cerebral Cortex and Liver During Chronic Ethanol Ingestion and WithdrawalPublished by Springer Nature ,1977
- Brain Catecholamines and Ethanol: Involvement in Physical Dependence and WithdrawalPublished by Springer Nature ,1977
- Importance of acetaldehyde in the action of ethanol on brain norepinephrine and 5-hydroxytryptamineBiochemical Pharmacology, 1966
- Ethanol and urinary catecholamines in manClinical Pharmacology & Therapeutics, 1965
- Ineffectiveness of Ethanol on Noradrenaline, Dopamine or 5‐Hydroxytryptamine Levels in BrainActa Pharmacologica et Toxicologica, 1961
- The urinary excretion of noradrenaline and adrenaline during acute alcohol intoxication in alcoholic addictsCellular and Molecular Life Sciences, 1960
- The Effect of Ethyl Alcohol on the Secretion from the Adrenal Medulla in Man.Acta Physiologica Scandinavica, 1958