The effects of ductal ligation on the parenchyma of salivary glands of cat studied by enzyme histochemical methods

Abstract

Submandibular, sublingual and parotid glands of cat have been studied following periods of ductal ligation ranging from 1 day to 1 year. An increased prominence of granules of acid phosphatase, β-glucuronidase and E600-resistant esterase reaction products was sometimes seen in acinar cells and atrophic striated ductal cells, and probably represents increased lysosomal enzymic activity, which may be of importance in the adaptation of the parenchyma to the altered environment. Other reaction products often appeared to be at normal levels in parenchymal structures that were not very atrophic, and at reduced levels in those that were very atrophic, suggesting a reduction of functional activity in these structures.