THE ANAMNESTIC ANTIBODY RESPONSE TO TYPE III SPECIFIC PNEUMOCOCCAL POLYSACCHARIDE
Open Access
- 1 July 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 130 (1), 77-89
- https://doi.org/10.1084/jem.130.1.77
Abstract
Rabbits immunized with killed type III pneumococci respond to anamnestic challenge by type specific polysaccharide (S III) with the synthesis of anti-S III antibody if a long interval is allowed to elapse between primary and secondary immunization. A study of the anti-S III antibody produced early and late in the immune response revealed no change in molecular class, banding pattern of dissociated light chains, or S III binding characteristics as measured under equilibrium conditions or by study of dissociation kinetics utilizing radioiodinated p-OH-benzyl-S III.Keywords
This publication has 14 references indexed in Scilit:
- CELL SEPARATION ON ANTIGEN-COATED COLUMNSThe Journal of Experimental Medicine, 1969
- Antibodies to Pneumococcal Polysaccharides: Relation between Binding and Electrophoretic HeterogeneityScience, 1968
- The immunogenicity of vinyl polymers.Proceedings of the National Academy of Sciences, 1968
- Sequence of Events in Mice Early in Immunologic Paralysis by Pneumococcal PolysaccharideThe Journal of Immunology, 1968
- SPECIFICITY OF CELLULAR IMMUNE RESPONSESThe Journal of Experimental Medicine, 1968
- SYNTHETIC ANTIGENS COMPOSED EXCLUSIVELY OF L- OR D-AMINO ACIDS .I. EFFECT OF OPTICAL CONFIGURATION ON IMMUNOGENICITY OF SYNTHETIC POLYPEPTIDES IN MICE1967
- STUDIES ON THE INDUCTION OF IMMUNOLOGICAL UNRESPONSIVENESS TO PNEUMOCOCCAL POLYSACCHARIDE IN MICEThe Journal of Experimental Medicine, 1966
- Electrophoretic Heterogeneity of Polypeptide Chains of Specific AntibodiesScience, 1966
- Variations in Affinities of Antibodies during the Immune Response*Biochemistry, 1964
- A QUANTITATIVE THEORY OF THE PRECIPITIN REACTIONThe Journal of Experimental Medicine, 1937