A Convenient Synthesis of 2-Acylmethyl-4,4-dimethyl-2-oxazolines. Useful Reagents for β-Keto Ester Synthesis
- 1 August 1984
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 57 (8), 2329-2330
- https://doi.org/10.1246/bcsj.57.2329
Abstract
Acylation of 2,4,4-trimethyl-2-oxazoline with acid chlorides having no α-proton and triethylamine gave C,N-diacylated products. Hydrolysis of the products with potassium hydroxide gave the enols of 2-acylmethyl-oxazolines, which were selectively C-monoalkylated by alkyl halides.This publication has 7 references indexed in Scilit:
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