Family of Large Surface Proteins on Human Lymphocytes

Abstract
Cells surface molecules of erythrocyte-rosette-positive human peripheral blood lymphocytes were labeled by lactoperoxidase and examined on 5% polyacrylamide gels. Several bands, ranging in MW from 220,000-170,000 daltons, were seen. Analysis of the tryptic and chymotryptic digests of the 187K, 200K, 210K and 220K proteins indicated that they are of similar peptide composition. Study of clones derived from this population indicated that individual cells within a population differed in expression of these proteins.