The Concentration of Free Meso-Inositol in the Plasma of Perfused Sheep Foetuses

Abstract

The free meso-inositol concentration in the plasma of the sheep fetus maintained after detachment from the placenta by an extracorporeal perfusion, was found to rise with time. The addition of glucose, fructose, acetate and acetoacetate did not appear to influence the rise of the plasma meso-inositol concentration. The production rate in terms of mg/kg body wt/h declined as term was approached.