Possible Teratogenic Effects of Veratramine

Abstract

Summary The alkaloid veratramine, a parent alkamine of the steroidal class of veratrum alkaloids, produced congenital abnormalities in lambs. It did not produce the expected cyclopian deformities but rather abnormalities which included slight lateral or medial bowing of the front legs, slight to marked flexure of knee joint, looseness of the hock or stifle joints, or complete lack of skeletal muscular control (inability to rise).