Successful Treatment with Voriconazole of Invasive Aspergillosis in Chronic Granulomatous Disease
- 1 May 1998
- journal article
- case report
- Published by American Thoracic Society in American Journal of Respiratory and Critical Care Medicine
- Vol. 157 (5), 1694-1696
- https://doi.org/10.1164/ajrccm.157.5.9709068
Abstract
A 5-year-old boy with chronic granulomatous disease (CGD) was treated with amphotericin B for an invasive pulmonary Aspergillus nidulans infection. The infection progressed during 6 wk of treatment despite the addition of interferon-gamma (IFN-gamma), filgrastim, and transfusions with donor granulocytes. Treatment with a novel antifungal triazole, voriconazole, resulted in an excellent clinical response.Keywords
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