DEMONSTRATION OF INTRACELLULAR CARRAGEENAN BY A FLUORESCENT ANTIBODY TECHNIQUE IN GRANULOMA TISSUE

Abstract

Intracellular localization of λ-carrageenan in the carrageenan granuloma has been demonstrated by a specific fluorescent antibody to the polymer. In general, the fluorescent antibody staining correlated with the intracellular metachromatic staining. The fluorescent antibody technique did not confirm that the extracellular metachromasia was due to λ-carrageenan.