Recovery of Motor Function after Spinal-Cord Injury — A Randomized, Placebo-Controlled Trial with GM-1 Ganglioside
Open Access
- 27 June 1991
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 324 (26), 1829-1838
- https://doi.org/10.1056/nejm199106273242601
Abstract
Spinal-cord injury is devastating; until recently, there was no medical treatment to improve recovery of the initial neurologic deficit. Studies in animals have shown that monosialotetrahexosylganglioside (GM-1) ganglioside enhances the functional recovery of damaged neurons.Keywords
This publication has 47 references indexed in Scilit:
- Correspondence NATIONAL ACUTE SPINAL CORD INJURY STUDY OF METHYLPREDNISOLONE OR NALOXONENeurosurgery, 1991
- A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord InjuryNew England Journal of Medicine, 1990
- Functional Outcome Following Spinal Cord InjuryArchives of Neurology, 1989
- Methylprednisolone and neurological function 1 year after spinal cord injuryJournal of Neurosurgery, 1985
- A Phase I trial of naloxone treatment in acute spinal cord injuryJournal of Neurosurgery, 1985
- Efficacy of methylprednisolone in acute spinal cord injuryJAMA, 1984
- Survival in traumatic spinal cord injurySpinal Cord, 1983
- Survival from spinal cord injuryJournal of Chronic Diseases, 1982
- INCIDENCE OF ACUTE TRAUMATIC HOSPITALIZED SPINAL CORD INJURY IN THE UNITED STATES, 1970–19771American Journal of Epidemiology, 1981
- Incidence of traumatic spinal cord lesionsJournal of Chronic Diseases, 1975