Synthesis of fluorinated branched-chain sugars

Abstract

Treatment of (E)-3-deoxy-3-C-ethoxycarbonyl(formylamino)methylene-1,2 : 5,6-di-O-isopropylidene-α-D-glucofuranose with trifluoro(fluoro-oxy)methane gives branched-chain sugars bearing a fluorine atom at the branch point. Some reactions of these fluorinated sugars are described.