Hepatic Necrosis in Rats Following Halothane Administration: Protective Effect of Diethyldithiocarbamate
- 1 October 1980
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 15 (7), 859-864
- https://doi.org/10.3109/00365528009181542
Abstract
Foci of necrosis were observed in the livers of 50% of enzyme-induced rats treated with halothane. The frequency of liver necrosis was significantly reduced by treatment with the free radical scavenger diethyldithiocarbamate. Severity of the lesion was not increased by repeated exposures to the anesthetic and although the frequency of liver necroses was greater, differences were not statistically significant.This publication has 19 references indexed in Scilit:
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