Inhibitor Studies on Light-Induced Phosphorylation in Extracts of Rhodospirillum rubrum.

Abstract

Light-induced phos-phorylation in extracts of the photosynthetic bacterium R. rubrum is strongly inhibited not only by 2-n-heptyl-4-hydroxyquinoline-N-oxide and antomyoin A but also by gramicidin and oligomycin A in concentrations which are similar to those necessary to inhibit the reactions involved in oxidative phosphorylation in animal mitochondria. Amytal, azide and cyanide have only a weak inhibitory effect. Dicumarol and especially 2,4-dinitrophenol which both "uncouple" phosphorylation from electron transport in animal mitochondria have a much less pronounced inhibitory effect on the light-induced phosphorylation.