Characterization of α‐adrenoceptors in the myocardium
Open Access
- 1 May 1973
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 48 (1), 132-138
- https://doi.org/10.1111/j.1476-5381.1973.tb08230.x
Abstract
1 In the driven rabbit left atrium α-adrenoceptors mediate the inotropic effect of phenylephrine and the prolongation of functional refractory period by sympathomimetic amines. 2 These receptors are highly sensitive to blockade by phentolamine and phenoxybenzamine. 3 Prolongation of functional refractory period is greater with the secondary amines, phenylephrine, adrenaline and epinine, than with the primary amines, norphenylephrine, noradrenaline and dopamine.Keywords
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