In the five years ending Jan. 1, 1926, 903 patients with gallbladder disease were admitted to the surgical service of the Lankenau Hospital. Of these, 605 (67 per cent)1 were female, and 298 (33 per cent) were male patients; 452 (50 per cent) were of the calculous and 438 (48.5 per cent) of the noncalculous variety. The series included also thirteen cases (1.5 per cent) of carcinoma of the gallbladder. Although most of the patients were admitted during a more or less quiescent interval, 149 (17.5 per cent of the total number) of the patients with calculous cholecystitis showed acute symptoms at the time of admission, as revealed by fever, tenderness, a palpable mass in the right upper abdomen, rigidity and a leukocytosis above 10,000. Of these, 114 were women and thirty-five men. Of the noncalculous variety, ninety-nine (9.8 per cent) were diagnosed as acute because of the same