Epidemics of Diarrhea Caused by a Clindamycin-Resistant Strain ofClostridium difficilein Four Hospitals
- 25 November 1999
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 341 (22), 1645-1651
- https://doi.org/10.1056/nejm199911253412203
Abstract
Large outbreaks of diarrhea caused by a newly recognized strain of Clostridium difficile occurred in four hospitals located in different parts of the United States between 1989 and 1992. Since frequent use of clindamycin was associated with the outbreak in one of the hospitals, we examined the resistance genes of the epidemic-strain isolates and studied the role of clindamycin use in these outbreaks.Keywords
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